Publication

  1. Gao J, Lu Y, Luo Y, Duan X, Chen P, Zhang X, Wu X, Qiu M, Shen W*. β-Catenin and SOX2 Interaction Regulate Visual Experience-Dependent Cell Homeostasis in the Developing Xenopus Thalamus. International Journal of Molecular Sciences. 2023; 24(17):13593. https://doi.org/10.3390/ijms241713593 [NCBI]

  2. Liao Y, Ma L, Guo Q, E W, Fang X, Yang L, Ruan F, Wang J, Zhang P, Sun Z, Chen H, Lin Z, Wang X, Wang X, Sun H, Fang X, Zhou Y, Chen M, Shen W. H.*, Guo G*, Han X*. Cell landscape of larval and adult Xenopus laevis at single-cell resolution. Nat Commun. 2022 Jul 25;13(1):4306. doi: 10.1038/s41467-022-31949-2. Erratum in: Nat Commun. 2022 Sep 1;13(1):5142. [NCBI]

  3. Mei R, Huang L, Wu M, Jiang C, Yang A, Tao H, Zheng K, Yang J, Shen W.H. ,Chen X, Zhao X, Qiu M. (2021). Evidence That ITPR2-Mediated Intracellular Calcium Release in Oligodendrocytes Regulates the Development of Carbonic Anhydrase II + Type I/II Oligodendrocytes and the Sizes of Myelin Fibers. Front Cell Neurosci. , 15:751439. [NCBI]

  4. Luo Y  Shen W. H.* ,Cline HT (2021). Electrophysiological Recording for Study of Xenopus Retinotectal Circuitry. Cold Spring Harb Protoc., (6):10. [NCBI]

  5. Gao J and Shen W. H.* (2021). Xenopus in revealing developmental toxicity and modeling human diseases. Environmental Pollution, 268: 115809 [NCBI]

  6. Gao J, Liao Y, Qiu M, Shen W. H.* (2020). Wnt/β-Catenin Signaling in Neural Stem Cell Homeostasis and Neurological Diseases. Neuroscientist. 1073858420914509. doi:10.1177/1073858420914509. [NCBI]  Shen lab[Full PDF]

  7. Liao Y, Luo Y, Ding N, Gao J, Wang X, Shen W. H.* (2020) .d-Glucuronolactone attenuates para-xylene-induced defects in neuronal development and plasticity in Xenopus tectum in vivo. Toxicology 430:152341. [NCBI]  Shen lab[Full PDF]

  8. He, H. Y., Shen W. H.*, Zheng, L., Guo X., & Cline, H. T* (2018). Cell-autonomous regulation of structural and functional plasticity in inhibitory neurons by excitatory synaptic inputs.  Nat. Commun. 9: 2893. [NCBI]  Shen lab[Full PDF]

  9. Liu, H. H., D. B. McClatchy, L. Schiapparelli, Shen W. H., J. R. Yates, 3rd and H. T. Cline* (2018). Role of the visual experience-dependent nascent proteome in neuronal plasticity. Elife 7. [Full PDF]

  10. Ruan, H., J. Gao, X. Qi, Y. Tao, X. Guo, Z. Guo, L. Zheng, Y. Song, Y. Liao and Shen W. H.* (2017). "Visual Experience Dependent Regulation of Neuronal Structure and Function by Histone Deacetylase 1 in Developing Xenopus Tectum in vivo." Dev Neurobiol. 77(8):947-962.  Shen lab[Full PDF]

  11. He, H. Y., Shen W. H., Hiramoto, M. & Cline, H. T* (2016). Experience-Dependent Bimodal Plasticity of Inhibitory Neurons in Early Development. Neuron 90, 1203-1214  Shen lab[Full PDF]

  12. Gao J, Ruan H, Qi X, Tao Y, Guo X, Shen W. H.* (2016). HDAC3 But not HDAC2 Mediates Visual Experience-Dependent Radial Glia Proliferation in the Developing Xenopus Tectum. Front Cell Neurosci.10:221. [Full PDF]

  13. Gao J, Ruan H, Qi X, Guo X, Zheng J, Liu C, Fang Y, Huang M, Xu M, Shen W. H.* (2016). Increased apoptosis and abnormal visual behavior by histone modifications with exposure to para-xylene in developing Xenopus. Neuroscience. 331:177-85. Shen lab[Full PDF]

  14. Guo, X., Ruan, H., Li, X., Qin, L., Tao, Y., Qi, X., Gao, J., Gan, L., Duan, S., and Shen, W. H.* (2016). "Subcellular Localization of Class I Histone Deacetylases in the Developing Xenopus tectum." Front Cell Neurosci. 9: 510. [Full PDF]

  15. Tao, Y., Ruan, H., Guo, X., Li, L.*, Shen, W. H.*. （2015）HDAC1 Regulates the Proliferation of Radial Glial Cells in the Developing Xenopus Tectum. PLoS ONE. 10(3):e0120118. [Full PDF]

  16. Shen W. H. #, Liu H.H., Schiapparelli L., McClatchy D., He H.Y., Yates JR. 3rd, Cline H.T.*（2014）Acute Synthesis of CPEB Is Required for Plasticity of Visual Avoidance Behavior in Xenopus. Cell Rep. 6(4), 737-47. [Full PDF]

  17. McKeown CR, Sharma P, Sharipov HE, Shen W. H., Cline HT.* (2013) Neurogenesis is required for behavioral recovery after injury in the visual system of Xenopus laevis. J Comp Neurol. 521(10), 2262-78. Shen lab[Full PDF]

  18. Shen, W. H. #, Mckeown, C., Demas, J., and Cline, H. T.* (2011) Inhibition to excitation ratio regulates  visual system responses and behavior in vivo, J. Neurophysiol. 106(5), 2285-302. Shen lab[Full PDF]

  19. Shen, W. H.#, Da Silva, J. S.#, He, H. Y, and Cline, H. T.* (2009) Type A GABA-receptor-dependent synaptic transmission sculpts dendritic arbor structure in Xenopus tadpoles in vivo, J. Neurosci. 29, 5032-5043. Shen lab[Full PDF]

  20. Ji Y.Y., Lu Y., Yang F., Shen W. H., Tang T.T., Feng L., Duan S., Lu B. (2010) Acute and gradual increases in BDNF concentration elicit distinct signaling and functions in neurons. Nat Neurosci. 13(3), 302-309. Shen lab[Full PDF]

  21. Chen, C. M., Chiu, S. L., Shen, W. H., and Cline, H. T.* (2009) Co-expression of Argonaute2 enhances short hairpin RNA-induced RNA interference in Xenopus CNS neurons in vivo, Frontiers Neurosci. 3, 63. [Full PDF]

  22. Tong, X. P., Li, X. Y., Zhou, B., Shen, W. H., Zhang, Z. J., Xu, T. L., and Duan, S. M.* (2009) Ca2+ signaling evoked by activation of Na+ channels and Na+/Ca2+ exchangers is required for GABA-induced NG2 cell migration, J. Cell Biol. 186, 113-128. Shen lab[Full PDF]

  23. Zheng, J., Shen, W. H., Lu, T. J., Zhou, Y., Chen, Q., Wang, Z., Xiang, T., Zhu, Y. C., Zhang, C., Duan, S. M., and Xiong, Z. Q.*(2008) Clathrin-dependent endocytosis is required for TrkB-dependent Akt-mediated neuronal protection and dendritic growth, J Biol Chem 283, 13280-13288. Shen lab[Full PDF]

  24. Yu, H.-M., Wen, J., Wang, R., Shen, W. H., Duan, S. M., and Yang, H.-T. * (2008) Critical role of type 2 ryanodine receptor in mediating activity-dependent neurogenesis from embryonic stem cells, Cell Calcium 43, 417-431. Shen lab[Full PDF]

  25. Shen, W. H. #, Wu, B.*, Zhang, Z. J., Dou, Y., Rao, Z. R., Chen, Y. R., and Duan, S. M.* (2006) Activity-induced rapid synaptic maturation mediated by presynaptic cdc42 signaling, Neuron 50, 401-414. (This article was featured on this month's NEURON cover and preview by Atasoy and Kavalali) Shen lab[Full PDF]

  26. Ge, W. P.#, Yang, X. J.#, Zhang, Z. J., Wang, H. K., Shen, W. H., Deng, Q. D., and Duan, S. M.* (2006) Long-term potentiation of neuron-glia synapses mediated by Ca2+-permeable AMPA receptors, Science 312, 1533-1537. Shen lab[Full PDF]

  27. Zhang, C. Y., Shen, W. H., and Zhang, G. Y.* (2004) Ischemia-induced release of cytochrome c from mitochondria and up-regulation of Bcl-2 expression in rat hippocampus, Sheng Li Xue Bao 56, 147-152.

  28. Yang, Y. L., Ge, W. P., Chen, Y. R., Zhang, Z. J., Shen, W. H., Wu, C. P., Poo, M. M., and Duan, S. M.* (2003) Contribution of astrocytes to hippocampal long-term potentiation through release of D-serine, Proc Natl Acad Sci U S A 100, 15194-15199. Shen lab[Full PDF]

  29. Shen, W. H., Zhang, C. Y., and Zhang, G. Y.* (2003) Modulation of IkappaB kinase autophosphorylation and activity following brain ischemia, Acta Pharmacol Sin 24, 311-315.

  30. Shen, W. H., Zhang, C. Y., and Zhang, G. Y.* (2003) Antioxidants attenuate reperfusion injury after global brain ischemia through inhibiting nuclear factor-kappa B activity in rats, Acta Pharmacol Sin 24, 1125-1130.

  31. Fu, Y., Pei, D. S., Sun, B., Shen, W. H., Lu, L., Hu, S. Q., and Zhao, H. R.* (2003) Identification of important amino acid residues for human IL-18 function by mutant construction, Acta Biochimica et Biophysica Sinica 35, 409-415.

  32. Zhang, C. Y., Shen, W. H., and Zhang, G. Y.* (2002) N-methyl-D-aspartate receptor and L-type voltage-gated Ca2+ channel antagonists suppress the release of cytochrome c and the expression of procaspase-3 in rat hippocampus after global brain ischemia, Neurosci Lett 328, 265-268.

  33. Shen, W. H., Zhang, C. Y., and Zhang, G. Y.* (2002) Nuclear factor kappaB activation is mediated by NMDA and non-NMDA receptor and L-type voltage-gated Ca2+ channel following severe global ischemia in rat hippocampus, Brain Res 933, 23-30.Shen lab[Full PDF]