Nucleic Acids Research

Nucleic Acids Research (Nucleic Acids Res, ISSN 0305-1048) is a fully open access, peer-reviewed journal published by Oxford University Press, widely regarded as one of the premier international periodicals in molecular biology and biochemistry. The journal’s scope encompasses all aspects of nucleic acids research, with a strong emphasis on the physical, chemical, biochemical, and biological properties of nucleic acids and their constituent nucleotides. Core topics include genome structure and function, DNA replication, repair, and recombination, RNA biology, transcription, translation, gene regulation, and the development of novel nucleic acid-based technologies, including CRISPR systems and synthetic biology tools. The journal publishes a range of article types, including original research articles, methods papers, and the highly influential annual Database Issue and Web Server Issue, which serve as essential resources for bioinformatics and computational biology. The primary target audience includes academic researchers, postdoctoral fellows, and graduate students working in molecular biology, genetics, genomics, and related life sciences. A notable feature of Nucleic Acids Research is its longstanding commitment to open access, ensuring all content is freely available upon publication. With a 2026 Impact Factor of 14.900 and consistently ranked in JCR Quartile 1 within the top-tier biology subject area (1区生物学), the journal holds exceptional standing in the field. Its high citation impact, rigorous peer review, and specialized focus on nucleic acids make it an indispensable platform for disseminating high-impact discoveries and methodological advances central to modern molecular life sciences.