Mechanisms of Ageing and Development

Mechanisms of Ageing and Development, abbreviated as Mech Ageing Dev and bearing the ISSN 0047-6374, is a premier international peer-reviewed journal dedicated to advancing the understanding of the biological mechanisms underlying the ageing process and age-related diseases. The journal’s scope encompasses fundamental and translational research exploring the molecular, cellular, genetic, and physiological pathways that drive ageing, including studies on cellular senescence, telomere biology, mitochondrial dysfunction, proteostasis, epigenetics, and stem cell ageing. It also covers the interplay between ageing and pathologies such as neurodegeneration, cardiovascular disease, cancer, and metabolic disorders, with a strong emphasis on mechanistic insights rather than purely descriptive observations. The journal publishes a diverse range of article types, including original research articles, comprehensive reviews, short communications, and special issues focused on emerging themes in geroscience. Its primary target audience comprises academic researchers, gerontologists, cell biologists, molecular geneticists, and clinicians interested in the fundamental biology of ageing. Published by Elsevier, the journal offers both subscription and open access options, allowing authors to choose the dissemination model that best suits their funding and visibility requirements. With an Impact Factor of 6.5000 in 2026, Mechanisms of Ageing and Development is firmly positioned in the JCR Q1 quartile, reflecting its high citation impact and significant influence within the fields of cell biology and gerontology. This standing underscores its reputation as a key resource for cutting-edge, high-quality research that elucidates the core mechanisms of ageing and informs future therapeutic strategies.